Case-control study of modifiable risk factors for congenital malformations
The aims of this project are:
- To investigate the associations between maternal and paternal occupational exposures and congenital malformations in New Zealand.
- To evaluate the contribution of non-occupational modifiable risk factors for CM including obesity, diabetes, alcohol consumption and folic acid supplementation.
- To assess the contributions of (i) acute exposures during the critical period around conception and (ii) chronic lifetime exposures to the risk of CM.
- To investigate the risk factors for specific CM subtypes.
- To estimate the fraction of CM cases that can be potentially prevented.
Data collection has now been completed.
RELATED PUBLICATIONS

't Mannetje A, Borman B, Eng A, Ellison-Loschmann L, Douwes J, Pearce N. Hair Dye Use and the Risk of Congenital Malformations. Results from a New Zealand Birth Defects Case-Control Study. Teratology Society 56th Annual Meeting, San Antonio, June 25-29 2016. Abstract 27 Platform Session 4. Birth Defects Research Part A (BDRA), 2016; 106(5): 398. |
![]() |