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Occupational exposure and brain cancer

The object of this project is to study the association of occupational EMF and chemical exposures and the risk of brain tumour, notably glioma and meningioma. A major weakness of earlier studies of occupational risk factors for brain cancer has been the difficulty in accruing sufficient numbers of cases in individual studies. Within the context of the recently completed international collaborative study of mobile phone use and brain tumours, the INTERPHONE study, coordinated by the International Agency for Research on Cancer occupational information has been collected for more than 10,000 subjects. The exploitation of this dataset to throw further light on the many putative occupational risk factors for brain cancer is an important research opportunity. It is hoped that the results from this project can be ultimately combined with those of the brain cancer study currently being conducted by Peter Inskip and colleagues at the NCI.

RELATED PUBLICATIONS

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van Tongeren M, Kincl L, Richardson L, Benke G, Figuerola A, Kauppinen T, Lakhani R, Lavoué J, McLean D, Plato N, Cardis E, for the INTEROCC Study Group . Assessing occupational exposure to chemicals in an international epidemiological study of brain tumours. Ann Occup Hyg, 2013; 57(5): 610-626.
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Lacourt A, Cardis E, Pintos J, Richardson L, Kincl L, Benke G, Fleming S, Hours M, Krewski D, McLean D, Parent M, Sadetzki S, Schlaefer K, Schlehofer B, van Tongeren M, Siemiatycki J. INTEROCC Study: association between glioma tumours and occupational exposure to selected combustion products, dusts and other chemical agents. BMC Public Health, 2013; 13: 340.
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Vila J, Bowman J, Richardson L, Kincl L, Conover D, McLean D, Mann S, Vecchia P, van Tongeren M, Cardis E. on behalf of the INTEROCC study group. A source-based measurement database for occupational exposure assessment of electromagnetic fields in the INTEROCC study: A literature review approach. Ann Occup Hyg, 2016; 60(2): 184-204. link icon
Benke G, Turner M, Fleming S, Figuerola J, Kincl L, Richardson L, Blettner M, Hours M, Krewski D, McLean D, Parent M, Sadetzki S, Schlaefer K, Schlehofer B, Siemiatycki J, van Tongeren M, Cardis E. Occupational solvent exposure and risk of glioma in the INTEROCC study. Br J Cancer, 2017; 117(8): 1246-1254. link icon
McElvenny D, van Tongeren M, Turner M, Benke G, Figuerola J, Fleming S, Hours M, Kincl L, Krewski D, McLean D, Parent M, Richardson L, Schlehofer B, Schlaefer K, Sadetzki S, Schüz J, Siemiatycki J, Cardis E. The INTEROCC case-control study: risk of meningioma and occupational exposure to selected combustion products, dusts and other chemical agents. Occup Environ Med, 2018; 75(1):12-22. link icon
Turner M, Benke G, Bowman J, Figuerola J, Fleming S, Hours M, Kincl L, Krewski D, McLean D, Parent M, Richardson L, Sadetzki S, Schlaefer K, Schlehofer B, Schüz J, Siemiatycki J, van Tongeren M, Cardis E. Interactions between occupational exposure to extremely low frequency magnetic fields and chemicals for brain tumour risk in the INTEROCC study. Occup Environ Med, 2017; 74(11): 802-809. link icon
Hinz R, 't Mannetje A, Glass B, McLean D, Pearce N, Douwes J. (2019) Fumigant and chemical residue 8-hour exposures in workers handling cargo from shipping containers and export logs in New Zealand. 27th International Symposium on Epidemiology in Occupational Health (EPICOH 2019). 29 Apr-2 May, Wellington, NZ. Occ Environ Med, 2019; 76(1): A9-A10. link icon

August 2008

RESEARCHERS

Dave

COLLABORATORS

  • Dr Geza Paul Benke
  • Monash University, Australia
  • A/P Marie-Elise Parent
  • Institut Armand Frappier, Canada
  • Ms Lesley Richardson
  • Canada
  • Prof. Jack Siemiatycki
  • Université de Montréal, Canada
  • Dr Timo Kauppinen
  • Finnish Institute of Occupational Health, Finland
  • Dr. Martine Hours
  • Unité Mixte de Recherche Transport Travail Environnement UCBL- INRETS, France
  • Dr. Brigitte Schlehofer
  • DKFZ German Cancer Research Center, Germany
  • Dr Avital Yarus Hakak
  • The Gertner Institute for Epidemiology and Health Policy Research, Israel
  • Dr. Siegal Sadetzki
  • The Gertner Institute for Epidemiology and Health Policy Research, Israel
  • Dr. Susanna Lagorio
  • Istituto Superiore di Sanita, Italy
  • Dr. Maria Feychting
  • Istituto Superiore di Sanita, Rome, Italy
  • Dr Nils Plato
  • Karolinska Institutet, Stockholm, Sweden
  • Dr Martie van Tongeren
  • Institute of Occupational Medicine, Riccarton, Edinburgh
  • Dr Joseph Bowman
  • NIOSH, Cincinnati, Ohio, USA
  • Dr David Conover
  • NIOSH, Cincinnati, Ohio, USA
  • Dr. Elisabeth Cardis
  • IARC, Lyon, France
  • Dr Isabelle Deltour
  • IARC, Lyon, France
  • Dr Isabelle Deltour
  • IARC, Lyon, France
  • Ms Monika Moissonnier
  • IARC, Lyon, France
  • Dr Martine Vrijheid
  • IARC, Lyon, France

FUNDING

  • International Agency for Research on Cancer (IARC)