Research Projects

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Case-control study of modifiable risk factors for congenital malformations

The aims of this project are:

  1. To investigate the associations between maternal and paternal occupational exposures and congenital malformations in New Zealand.
  2. To evaluate the contribution of non-occupational modifiable risk factors for CM including obesity, diabetes, alcohol consumption and folic acid supplementation.
  3. To assess the contributions of (i) acute exposures during the critical period around conception and (ii) chronic lifetime exposures to the risk of CM.
  4. To investigate the risk factors for specific CM subtypes.
  5. To estimate the fraction of CM cases that can be potentially prevented.

RELATED PUBLICATIONS

link icon
't Mannetje A, Borman B, Eng A, Ellison-Loschmann L, Douwes J, Pearce N. Hair Dye Use and the Risk of Congenital Malformations. Results from a New Zealand Birth Defects Case-Control Study. Teratology Society 56th Annual Meeting, San Antonio, June 25-29 2016. Abstract 27 Platform Session 4. Birth Defects Research Part A (BDRA), 2016; 106(5): 398. link icon

July 2008

COLLABORATORS

  • Dr Joanne Dixon
  • Wellington Hospital
  • Professor Innes Asher
  • Auckland Medical School

FUNDING

  • Health Research Council of New Zealand